Abstract A five-coordinate monomeric Cu(II) complex, 2([Cu(hydeten)2]·smz2)·na·5H2O (Hsmz: sulfamethazine, hydeten: N-(2-hydroxyethyl)-ethylenediamine and na; nicotinamide), has been synthesized and characterized by elemental analysis, X-ray diffraction techniques, IR, EPR and UV-vis spectroscopies. In the X-ray structural analysis, the copper atom is coordinated to two hydeten ligands, one of which is a triple and the other is a bilateral. Thus, it has two five-coordinate copper central cations which exhibit a distorted square-pyramidal geometry (τ = 0.23). The charge equivalence of the molecule is provided by the four sulfamethazine ligands which are deprotonated. The powder EPR spectra of the Cu(II) complex at room temperature and in liquid nitrogen were recorded. Based on EPR and optical absorption studies, spin-Hamiltonian and bonding parameters have been calculated and indicated the presence of the unpaired electron in the dx2-y2 orbital. Antimicrobial activity studies of the synthesized compound were investigated against S. aureus, B. subtilis, P. aeruginosa, E. coli, C. albicans and A. flavus by using the microdilution method. Graphical Abstract

中文翻译：

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Cu(II)-磺胺二甲嘧啶与 N-(2-羟乙基)-乙二胺的复合物：合成、光谱、结构表征和抗菌活性

摘要 一种五配位单体Cu(II)配合物，2([Cu(hydeten)2]·smz2)·na·5H2O（Hsmz：磺胺二甲嘧啶，hydeten：N-（2-羟乙基）-乙二胺和na；烟酰胺），已通过元素分析、X 射线衍射技术、IR、EPR 和 UV-vis 光谱合成和表征。在 X 射线结构分析中，铜原子与两个氢配体配位，其中一个是三元组，另一个是双侧的。因此，它具有两个五配位铜中心阳离子，它们表现出扭曲的方形锥体几何形状（τ = 0.23）。分子的电荷等价性由四个去质子化的磺胺二甲嘧啶配体提供。记录了 Cu(II) 配合物在室温和液氮中的粉末 EPR 光谱。基于 EPR 和光吸收研究，计算了自旋哈密顿和键合参数，并表明 dx2-y2 轨道中存在未成对电子。通过使用微量稀释方法研究了合成化合物对金黄色葡萄球菌、枯草芽孢杆菌、铜绿假单胞菌、大肠杆菌、白色念珠菌和黄曲霉的抗菌活性研究。图形概要