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A Multi‐Signaling Performance for Simultaneous Surveillance and Accretion of Cysteine and Serine in Human Cancer Cell
Asian Journal of Organic Chemistry ( IF 2.7 ) Pub Date : 2019-12-27 , DOI: 10.1002/ajoc.201900722
Shampa Kundu 1 , Pulak Kumar Maiti 2 , Prithidipa Sahoo 1
Affiliation  

A unique fluorescence chemosensing method has been introduced to explain a new strategy for simultaneous selective determination of cysteine and serine in two different emission channels through an “on–off–on” mechanism. Dansyl chloride‐picolylamine conjugate (DNPC) ensembles with Cu2+ (DNPC‐Cu2+) shows turn on fluorescence while binding with serine or cysteine. The chemosensing method has been successfully applied in human cancer cells to detect and quantify Cysteine and Serine differentially. More information can be found in the Full Paper by Shampa Kundu, Pulak Kumar Maiti, and Prithidipa Sahoo.
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中文翻译:

人癌细胞中半胱氨酸和丝氨酸同时监测和增生的多信号性能

引入了独特的荧光化学传感方法,以解释通过“开-关-开”机制同时选择性测定两个不同发射通道中半胱氨酸和丝氨酸的新策略。与Cu 2+(DNPC-Cu 2+)组合的Dansyl chloride-picolylamine缀合物(DNPC)在与丝氨酸或半胱氨酸结合的同时显示开启荧光。化学传感方法已成功应用于人类癌细胞中,以差异方式检测和定量半胱氨酸和丝氨酸。可以在Shampa Kundu,Pulak Kumar Maiti和Prithidipa Sahoo撰写的全文中找到更多信息。
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更新日期:2019-12-27
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