当前位置: X-MOL 学术Trends Parasitol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Targeting Plasmodium Plasmepsin V: Hitting Two Birds with One Stone.
Trends in Parasitology ( IF 9.6 ) Pub Date : 2020-02-01 , DOI: 10.1016/j.pt.2019.12.006
Nicolas M B Brancucci 1 , Volker T Heussler 2 , Christof Grüring 2
Affiliation  

A recent report by Jennison et al. reveals an important role for plasmepsin V (PMV), an aspartyl protease, in the development of malaria transmission stages. The authors showed that PMV activity is critical for protein export in these stages and that specific PMV inhibitors block parasite transmission to mosquitoes.

中文翻译:

靶向疟原虫溶血素V:用一只石头击中两只鸟。

Jennison等人的最新报告。揭示了纤溶酶V(PMV)(一种天冬氨酰蛋白酶)在疟疾传播阶段的发展中的重要作用。作者表明,PMV活性对于这些阶段的蛋白质输出至关重要,并且特定的PMV抑制剂可阻止寄生虫传播至蚊子。
更新日期:2019-12-27
down
wechat
bug