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Restoration of somatosensory function by pairing vagus nerve stimulation with tactile rehabilitation
Annals of Neurology ( IF 11.2 ) Pub Date : 2020-01-07 , DOI: 10.1002/ana.25664
Michael J Darrow 1, 2 , Tabarak M Mian 1, 3 , Miranda Torres 1, 3 , Zainab Haider 1, 3 , Tanya Danaphongse 1 , Robert L Rennaker 1, 2, 3 , Michael P Kilgard 1, 2, 3 , Seth A Hays 1, 2, 3
Affiliation  

Sensory dysfunction is a common consequence of many forms of neurological injury, including stroke and nerve damage. Rehabilitative paradigms that incorporate sensory retraining can provide modest benefits, but the majority of patients are left with lasting sensory loss. We have developed a novel strategy that uses closed‐loop vagus nerve stimulation (VNS) paired with tactile rehabilitation to enhance synaptic plasticity and facilitate recovery of sensory function.

中文翻译:

迷走神经刺激与触觉康复相结合恢复体感功能

感觉功能障碍是多种形式的神经损伤的常见后果,包括中风和神经损伤。包含感觉再训练的康复模式可以提供适度的益处,但大多数患者会留下持久的感觉丧失。我们开发了一种新策略,使用闭环迷走神经刺激 (VNS) 与触觉康复相结合,以增强突触可塑性并促进感觉功能的恢复。
更新日期:2020-01-07
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