Point-of-care testing (POCT), defined as the test performed at or near a patient, has been evolving into a complement to conventional laboratory diagnosis by continually providing portable, cost-effective, and easy-to-use measurement tools. Among them, microneedle-based POCT devices have gained increasing attention from researchers due to the glorious potential for detecting various analytes in a minimally invasive manner. More recently, a novel synergism between microneedle and wearable technologies is expanding their detection capabilities. Herein, we provide an overview on the progress in microneedle-based transdermal biosensors. It covers all the main aspects of the field, including design philosophy, material selection, and working mechanisms as well as the utility of the devices. We also discuss lessons from the past, challenges of the present, and visions for the future on translation of these state-of-the-art technologies from the bench to the bedside.

中文翻译：

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用于经皮诊断的微针：最新进展和新视野。

即时检验（POCT）是指在患者身上或附近进行的测试，它通过不断提供便携式，经济高效且易于使用的测量工具，已发展成为常规实验室诊断的补充。其中，基于微针的POCT设备因其以微创的方式检测各种分析物的巨大潜力而​​受到研究人员的越来越多的关注。最近，微针和可穿戴技术之间的新型协同作用正在扩展其检测能力。在这里，我们提供了基于微针的透皮生物传感器的进展的概述。它涵盖了该领域的所有主要方面，包括设计理念，材料选择，工作机制以及设备的实用性。我们还将讨论过去的经验教训，