Spatial navigation is influenced by cues from nearly every sensory modality and thus provides an excellent model for understanding how different sensory streams are integrated to drive behavior. Here we review recent work on multisensory control of navigation in the model organism Drosophila melanogaster, which allows for detailed circuit dissection. We identify four modes of integration that have been described in the literature-suppression, gating, summation, and association-and describe regions of the larval and adult brain that have been implicated in sensory integration. Finally we discuss what circuit architectures might support these different forms of integration. We argue that Drosophila is an excellent model to discover these circuit and biophysical motifs.

中文翻译：

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果蝇导航的多感官控制。

空间导航受到几乎所有感官模式的线索的影响，因此为理解不同的感官流如何整合以驱动行为提供了一个很好的模型。在这里，我们回顾了模型生物黑腹果蝇中导航的多感官控制的最新工作，它允许详细的电路解剖。我们确定了文献中描述的四种整合模式——抑制、门控、求和和关联——并描述了与感觉整合有关的幼虫和成虫大脑区域。最后，我们讨论哪些电路架构可能支持这些不同形式的集成。我们认为果蝇是发现这些电路和生物物理图案的绝佳模型。