An efficient, green strategy to access to a new series of quinolinthiones was investigated. The targeted derivatives have been prepared from arylhydrazides and 2-thiocoumarin under ultrasound irradiation in refluxing water. The remarkable features of this strategy are simple procedure, high conversion, cleaner with short reaction times. All resultant compounds were screened against bacterial strains for in vitro anti-bacterial activity. Derivative (6b) was showed highest potency with 22 and 24 mm inhibition zone against Staphylococcus aureus (Sa) and Escherichia coli (Ec), respectively.

中文翻译：

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新的喹啉-2-硫酮衍生物的超声加速绿色合成及其对大肠杆菌和金黄色葡萄球菌的抗菌评价

研究了一种有效的绿色策略，以获取一系列新的喹啉硫酮。该目标衍生物是由芳基酰肼和2-硫香豆素在回流水中超声辐照下制备的。该策略的显着特征是操作简单，转化率高，反应时间短的清洁剂。针对细菌菌株筛选所有所得化合物的体外抗菌活性。衍生物（6b）显示出对金黄色葡萄球菌（Sa）和大肠杆菌（Ec）分别具有22和24 mm抑制区的最高效力。