Sporopollenin sporoderm microcapsules (S-SMCs) are readily extracted from plant pollen grains and provide a renewable, biocompatible source of robust microparticles for a wide range of potential applications. While the lipidic/aromatic sporopollenin copolymer surface results in a predominantly hydrophobic interface, herein, we demonstrate how ultraviolet/ozone (UV-O) light-induced tuning of S-SMC interfacial properties enables production of hydrophobic to superhydrophilic microparticles, along with programmable function for colloidal science and cellular applications. In oil/water systems, stable Pickering emulsions are achieved using S-SMCs with short duration UV-O treatment, while incorporation of superhydrophilic S-SMCs into oil/water systems provides a novel means to produce, and isolate, fully oil-loaded microparticles. Furthermore, it is shown that human cells adhere to S-SMCs acting as tissue seeds, with the controllable formation of either 3D cell spheroids or network structures. Collectively, our findings demonstrate that light-induced modification of S-SMCs has broad implications across colloidal science, microencapsulation, drug delivery, and cellular applications.

孢粉蛋白孢子囊微胶囊（S-SMCs）可以很容易地从植物花粉粒中提取出来，并为广泛的潜在应用提供了可再生的，生物相容的坚固的微粒来源。虽然脂质/芳香族孢粉蛋白共聚物表面会形成主要的疏水界面，但在本文中，我们展示了紫外线/臭氧（UV-O）光诱导的S-SMC界面性质的调节如何使疏水性变为超亲水性微粒以及可编程功能用于胶体科学和细胞应用。在油/水系统中，使用短时间的UV-O处理的S-SMC可实现稳定的Pickering乳液，而将超亲水S-SMC掺入油/水系统则提供了一种生产和分离充满油的微粒的新颖方法。此外，结果表明，人类细胞粘附于充当组织种子的S-SMC上，并且可控地形成3D细胞球体或网络结构。总的来说，我们的研究结果表明，光诱导的S-SMC修饰对胶体科学，微囊化，药物递送和细胞应用具有广泛的影响。