Abstract Natural products-mediated synthesis has become quite an interesting route for the ecofriendly production of nanomaterials. However, products employed in natura may require long reaction times and high temperatures that lead to non-ideal particle-size distribution. In this work, we developed an optimized one-pot synthesis of silver nanoparticles using isolated ricinoleic acid (extracted from castor bean plant) and its epoxidized form as both reducer and stabilizer agents to convert silver ions into silver nanoparticles at room temperature. Through a design of experiments, we discovered that the epoxidized form of the ricinoleic acid is far more effective than its unmodified counterpart in terms of reaction time and homogeneity of nanoparticles. The silver nanoaparticles were then evaluated as functional chromogenic probes for cysteine sensing, allowing for direct naked-eye detection and a limit of detection of 25.37 μmol L−1. Cysteine sensing mechanisms are also discussed in this work. This approach reinforces the advantages in using purified natural products over their direct natural sources.

中文翻译：

---

蓖麻油衍生物在银纳米粒子的环保一锅法合成中的应用：在半胱氨酸传感中的应用

摘要 天然产物介导的合成已成为纳米材料生态友好生产的一条非常有趣的途径。然而，natura 中使用的产品可能需要较长的反应时间和高温，从而导致不理想的粒度分布。在这项工作中，我们使用分离的蓖麻油酸（从蓖麻植物中提取）及其环氧化形式作为还原剂和稳定剂开发了银纳米颗粒的优化一锅法合成，以在室温下将银离子转化为银纳米颗粒。通过实验设计，我们发现蓖麻油酸的环氧化形式在反应时间和纳米粒子的均匀性方面比未修饰的对应物更有效。然后将银纳米颗粒评估为用于半胱氨酸传感的功能显色探针，允许直接肉眼检测和 25.37 μmol L-1 的检测限。在这项工作中还讨论了半胱氨酸传感机制。这种方法加强了使用纯化天然产品优于直接天然来源的优势。