Evaluating mechanical properties of biological soft tissues and viscous mucus is challenging because of complicated dynamic behaviors. Soft condensed matter models have been successfully used to explain a number of dynamical behaviors. Here, we reported that optical coherence elastography (OCE) is capable of quantifying mechanical properties of soft condensed matters, micellar fluids. A 7.5 MHz focused transducer was utilized to generate acoustic radiation force exerted on the surface of soft condensed matters in order to produce Rayleigh waves. The waves were recorded by optical coherence tomography (OCT). The Kelvin‐Voigt model was adopted to evaluate shear modulus and loss modulus of soft condensed matters. The results reported that various concentrations of micellar fluids can provide reasonable ranges of elasticity from 65.71 to 428.78 Pa and viscosity from 0.035 to 0.283 Pa·s, which are close to ranges for actual biological samples, like mucus. OCE might be a promising tool to differentiate pathologic mucus samples from healthy cases as advanced applications in the future.

中文翻译：

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声辐射力光学相干弹性成像评价软凝聚态物质的力学性能及其生物学应用。

由于复杂的动态行为，评估生物软组织和粘液的机械特性具有挑战性。软凝聚态模型已成功用于解释许多动力学行为。在这里，我们报道了光学相干弹性成像（OCE）能够量化软凝聚态物质、胶束流体的机械性能。利用 7.5 MHz 聚焦换能器产生施加在软凝聚态物质表面的声辐射力，以产生瑞利波。这些波是通过光学相干断层扫描（OCT）记录的。采用Kelvin-Voigt模型来评估软凝聚态物质的剪切模量和损耗模量。结果表明，不同浓度的胶束流体可以提供合理的弹性范围（65.71 至 428.78 Pa）和粘度范围（0.035 至 0.283 Pa·s），这些范围接近实际生物样品（如粘液）的范围。OCE 可能是区分病理粘液样本与健康病​​例的有前途的工具，作为未来的高级应用。