Naegleria fowleri is responsible for the disease called primary amoebic meningoencephalitis (PAM). The infection is fatal in 98% of cases. The amoeba lives in warm, fresh water and enters the human brain through the nose, possibly during water activity or ablution for religious purposes. This amoeba is an emerging problem in Karachi, which is a major metropolitan city and coastal site of Pakistan. The first case of PAM was reported in 2008, and up until October, 2019, 146 cases had been reported from Karachi. In only a decade, the number of PAM cases in Pakistan exceeded those reported in the USA in half a century (ie, 142 cases between 1968 and 2019). The highest number of PAM cases in the USA were reported in children younger than 14 years, but in Pakistan, most cases are reported in adults aged 26–45 years, which points to the possibility of a genetically unique strain in Pakistan.

中文翻译：

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Naegleria fowleri在巴基斯坦。

鸡血藤负责称为原发性阿米巴脑膜脑炎（PAM）的疾病。在98％的病例中，感染是致命的。变形虫生活在温暖的淡水中，并可能通过水运动或出于宗教目的的沐浴而通过鼻子进入人脑。这种变形虫是卡拉奇的一个新出现的问题，卡拉奇是巴基斯坦的主要都会城市和沿海地区。PAM的第一例报告于2008年，截至2019年10月，卡拉奇报告了146例。在仅十年的时间里，巴基斯坦的PAM案例数量就超过了半个世纪以来美国的报告数量（即1968年至2019年之间有142例案例）。在美国，报道最多的PAM病例是14岁以下的儿童，但是在巴基斯坦，大多数病例报道的是26-45岁的成年人，