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One foot in the door: gene gating supports nuclear export of MYC mRNA.
Nature Reviews Cancer ( IF 78.5 ) Pub Date : 2019-12-24 , DOI: 10.1038/s41568-019-0236-3
Ulrike Harjes 1
Affiliation  

Gene gating is the tethering of genes to nuclear pores to facilitate rapid nuclear export of transcripts. Scholz et al. show that gene gating of MYC increases nuclear export and overall expression of MYC transcripts in human colon cancer cells.

中文翻译:

一只脚踩到门:基因门控支持MYC mRNA的核输出。

基因门控是将基因束缚到核孔中,以促进转录本的快速核输出。Scholz等。表明MYC的基因门控增加了人结肠癌细胞中核输出和MYC转录本的总体表达。
更新日期:2019-12-24
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