Hypertension, a multifactorial disorder resulting from the interplay between genetic predisposition and environmental risk factors, affects ≈30% of adults. Emerging evidence has shown that nonalcoholic fatty liver disease (NAFLD), as an underestimated metabolic abnormality, is strongly associated with an increased risk of incident prehypertension and hypertension. However, the role of NAFLD in the development of hypertension is still obscure and is highly overlooked by the general public. Herein, we highlight the epidemiological evidence and putative mechanisms focusing on the emerging roles of NAFLD in hypertension, with the purpose of reinforcing the notion that NAFLD may serve as an independent risk factor and an important driving force in the development and progression of hypertension. Finally, we also briefly summarize the current potential treatments for NAFLD that might also be beneficial approaches against hypertension.

中文翻译：

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非酒精性脂肪肝

高血压是一种由遗传易感性和环境风险因素相互作用引起的多因素疾病，影响约 30% 的成年人。新出现的证据表明，非酒精性脂肪肝 (NAFLD) 作为一种被低估的代谢异常，与高血压前期和高血压的风险增加密切相关。然而，NAFLD在高血压发展中的作用仍不清楚，被公众高度忽视。在此，我们重点关注 NAFLD 在高血压中的新作用的流行病学证据和推定机制，目的是强化 NAFLD 可能作为独立危险因素和高血压发展和进展的重要驱动力的概念。最后，