Coumarin-3-thioformates acting as a new type of 3-carbon partner were firstly prepared and engaged in reacting with 3-hydroxyoxindoles and 3-aminooxindoles by using DABCO or Et₃N as the catalyst. A wide scope of structurally diverse spiro-fused pentaheterocyclic compounds including spiro-butyrolactoneoxindole[3,4-c]coumarins and spiro-butyrolactamoxindole[3,4-c]coumarins, which combined oxindole, dihydrofuranone or pyrrolidone, and coumarin in one molecule, could be smoothly obtained in high yields via a tandem Michael addition–lactonization/lactamization process under mild conditions.

中文翻译：

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香豆素-3-硫代甲酸酯与3-羟基氧吲哚和3-氨基氧吲哚的环缩合反应用于合成螺环稠合的五杂环化合物

首先制备了作为新型的3-碳伙伴的香豆素-3-硫代甲酸酯，并通过使用DABCO或Et ₃ N作为催化剂使其与3-羟基氧吲哚和3-氨基氧吲哚反应。多种结构多样的螺稠合五杂环化合物，包括螺-丁内酯-羟吲哚[3,4- c ]香豆素和螺-丁内酯-肟基吲哚[3,4- c ]香豆素，它们在一个分子中结合了吲哚，二氢呋喃酮或吡咯烷酮和香豆素，在温和条件下，可通过串联的迈克尔加成-内酰胺化/内酰胺化工艺顺利地以高收成率顺利获得。