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Endfoot regrowth for neural stem cell renewal.
Nature Cell Biology ( IF 21.3 ) Pub Date : 2019-12-23 , DOI: 10.1038/s41556-019-0448-5
Masafumi Tsuboi 1 , Yukiko Gotoh 2, 3
Affiliation  

Tangential expansion of neural stem cells in the mammalian neocortex increases the number of cortical columns. A new study shows that neural stem cells that become detached from the apical surface during division regenerate an apical endfoot to ensure tangential expansion in the early stage but later lose this ability when radial expansion occurs.

中文翻译:

足底再生长用于神经干细胞更新。

哺乳动物新皮层中神经干细胞的切向扩展增加了皮层列的数量。一项新研究表明,神经干细胞在分裂过程中从根尖表面脱离,可再生一个根尖端脚,以确保在早期切向扩张,但后来在发生径向扩张时失去这种能力。
更新日期:2019-12-23
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