Three new meroterpenoids, asperaustins A-C (1-3), and seven known analogues (4-10) were isolated from a marine-derived Aspergillus sp. fungus. The structures and absolute configurations of these new compounds were unequivocally determined by extensive spectroscopic analyses and single-crystal X-ray diffraction analyses. Asperaustin A (1) possesses an unusual spiro[4.5]deca-3,6-dien-2-one moiety with a unique 5/6/6/6/5 pentacyclic skeleton. The absolute configurations of austinoneol A (7) and precalidodehydroaustin (9) were determined by single-crystal X-ray diffraction analyses using Cu Kα radiation for the first time.

中文翻译：

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来自海洋的曲霉菌的结构多样的类萜。菌。

从海洋来源的曲霉菌中分离出了三种新的类胡萝卜素类化合物，曲霉菌素AC（1-3）和七个已知的类似物（4-10）。菌。这些新化合物的结构和绝对构型是通过广泛的光谱分析和X射线单晶衍射分析明确确定的。Asperaustin A（1）具有不寻常的螺[4.5] deca-3,6-dien-2-one部分，具有独特的5/6/6/6/5五环骨架。首次使用CuKα射线通过单晶X射线衍射分析确定了奥斯汀酚A（7）和前加氢十二烷基氢化奥斯汀（9）的绝对构型。