An efficient one‐pot three‐component reaction of 4‐benzoyl‐5‐phenylamino‐2,3‐dihydrothiophene‐2,3‐dione, diaminomaleonitrile, and alcohols with hetero‐atom substituents or several hydroxyl groups in acetonitrile solvent under reflux led to the formation of 5‐(2‐substituted ethoxy or propoxy‐2‐phenyl‐1‐N‐phenylthiocarbamoylethenyl)‐6‐oxo‐1,6‐dihydropyrazine‐2,3‐dicarbonitrile derivatives in good yields.

中文翻译：

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通过4-苯甲酰基-5-苯基氨基-2-，3-二氢噻吩-2-，3-二酮，二氨基马来腈和官能化醇在乙腈中的一锅三组分反应合成吡嗪-2-3-二甲腈

乙腈溶剂中4-苯甲酰基-5-苯基氨基-2-，3-二氢噻吩-2-，3-二酮，二氨基马腈和带有杂原子取代基或多个羟基的醇的高效一锅三组分反应导致回流以高收率形成5-（2-取代的乙氧基或丙氧基-2--苯基-1- N-苯基硫代氨基甲酰基乙烯基）-6-氧代-1,6-二氢吡嗪-2,3-二碳腈衍生物。