当前位置: X-MOL 学术Exp. Gerontol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Comparison of age-specific leg extensor muscle function torque-time and rapid velocity attributes across the adult lifespan: A relative deficiency investigation.
Experimental Gerontology ( IF 3.9 ) Pub Date : 2019-12-20 , DOI: 10.1016/j.exger.2019.110819
Brennan J Thompson 1 , Eric J Sobolewski 2 , Eric D Ryan 3
Affiliation  

The purposes of this study were to examine the age-related differences in absolute and normalized torque-time parameters in five distinct groups across the adult lifespan, and the relationship between rapid strength and limb acceleration capacities across the lifespan. One-hundred and thirty-six healthy men were categorized as young athletes (n = 27; age = 20.7 yrs), young controls (n = 32; 21.9 yrs), middle young (n = 32; 49.8 yrs), middle old (n = 15; 58.9 yrs), and old (n = 30; 71.3 yrs) cohorts. Participants performed maximal voluntary contractions (MVCs) of the leg extensors under isometric and isokinetic (240 deg.·s-1) conditions. Outcome measures included peak torque (PT), absolute and MVC normalized (norm) rate of torque development (RTD) at 50 and 200 ms, RTD50/PT ratio, and rate of velocity development (RVD). The PT and absolute RTD at 200 ms declined from young to old age (P < .05). The middle age groups exhibited an overall preservation of early RTD, and a potential enhancement of early normalized RTD (P = .06 for middle young vs. controls, for RTDnorm50). The RTD50/PT ratio was higher in the middle young (P < .05) compared to both the young groups. Generally, the RVD declined more linearly and exhibited worse preservation at mid-life than the early absolute or normalized RTD variables. All absolute torque-time variables were correlated (r = 0.43-0.73, P < .001) to the RVD for all groups combined. These findings showed distinct age-related declines occurred for different muscle function parameters unique to specific stages of the lifespan. Normalized RTD variables may reveal plausible mechanisms of age-related neuromuscular changes and the RTD50/PT ratio may be a useful tool for determining relative deficiencies, such that mid-life adults (45-64 yrs) should address their relative limitation of PT by enhancing strength at mid-life, whereas older adults (65+ yrs) may need more emphasis on RTD improvements. In addition, both mid-life and older men should seek to improve rapid limb velocity capacities due to the susceptibility of RVD to decline more incrementally across the lifespan. Such information may help to improve anti-aging strategies by countering age-specific muscle function deficiencies and may improve mid-life adults' ability to transition better functionally into old age.

中文翻译:

在成年人的寿命中,特定年龄段的腿伸肌功能扭矩时间和快速速度属性的比较:相对缺陷调查。

这项研究的目的是检查成年人寿命中五个不同组中与年龄相关的绝对时间和标准化扭矩时间参数的差异,以及寿命中快速强度和肢体加速能力之间的关系。一百三十六名健康男性被分类为年轻运动员(n = 27;年龄= 20.7岁),年轻对照(n = 32; 21.9岁),中青年(n = 32; 49.8岁),中年( n = 15; 58.9岁)和年龄较大的人群(n = 30; 71.3岁)。参与者在等距和等速运动(240度·s-1)下进行了腿部伸肌的最大自愿收缩(MVC)。结果测量包括峰值转矩(PT),在50和200 ms时的转矩发展(RTD)的绝对和MVC标准化(正常)速率,RTD50 / PT比以及速度发展(RVD)。PT和绝对RTD在200毫秒时从年轻到老年下降(P <.05)。中年组表现出早期RTD的总体保留,以及早期标准化RTD的潜在增强(中青年vs.对照组,RTDnorm50为P = .06)。与两个年轻人组相比,中年年轻人的RTD50 / PT比更高(P <.05)。通常,与早期绝对或标准化RTD变量相比,RVD在中年期的下降趋势更线性,并且表现出更差的保存性。对于所有组合的组,所有绝对转矩时间变量都与RVD相关(r = 0.43-0.73,P <.001)。这些发现表明,针对寿命特定阶段所独有的不同肌肉功能参数,出现了与年龄相关的明显下降。标准化的RTD变量可能揭示与年龄有关的神经肌肉变化的合理机制,RTD50 / PT比可能是确定相对缺陷的有用工具,因此中年成年人(45-64岁)应通过增强其来解决PT的相对局限性中年强度,而老年人(65岁以上)可能需要更多地强调RTD的改善。此外,由于RVD易感性在整个寿命期内逐渐下降,因此中年和老年男性均应寻求提高肢体快速运动能力。此类信息可通过对抗特定年龄的肌肉功能缺陷来帮助改善抗衰老策略,并可能提高中年成年人从功能上更好地过渡到老年的能力。因此,中年成年人(45-64岁)应该通过增强中年人的力量来解决PT的相对局限性,而老年人(65岁以上)可能需要更加重视RTD的改善。此外,由于RVD易感性在整个寿命期内逐渐下降,因此中年和老年男性都应设法提高肢体的快速运动能力。此类信息可通过对抗特定年龄的肌肉功能缺陷来帮助改善抗衰老策略,并可能提高中年成年人从功能上更好地过渡到老年的能力。因此,中年成年人(45-64岁)应该通过增强中年人的力量来解决PT的相对局限性,而老年人(65岁以上)可能需要更加重视RTD的改善。此外,由于RVD易感性在整个寿命期内逐渐下降,因此中年和老年男性均应寻求提高肢体快速运动能力。此类信息可通过对抗特定年龄的肌肉功能缺陷来帮助改善抗衰老策略,并可能提高中年成年人从功能上更好地过渡到老年的能力。由于RVD易感性在整个寿命期内逐渐下降,因此中年和老年男性均应寻求提高快速肢体速度的能力。此类信息可通过对抗特定年龄的肌肉功能缺陷来帮助改善抗衰老策略,并可能提高中年成年人从功能上更好地过渡到老年的能力。由于RVD易感性在整个寿命期内逐渐下降,因此中年和老年男性均应寻求提高快速肢体速度的能力。此类信息可通过对抗特定年龄的肌肉功能缺陷来帮助改善抗衰老策略,并可能提高中年成年人从功能上更好地过渡到老年的能力。
更新日期:2019-12-20
down
wechat
bug