Mussel-inspired polymers attract much research interest due to their potential as effective adhesives. In this work, a new kind of mussel-inspired polymer, poly(dopamine phosphonate-co-PEGMA), is prepared via a one-pot multicomponent polymerization system. The multicomponent polymerization system refers to a combination of multicomponent Kabachnik-Fields (KF) reaction and reversible addition-fragmentation chain transfer (RAFT) polymerization system. Reactants are converted to dopamine phosphonate monomers in situ through the KF reaction and polymerized simultaneously along with poly(ethylene glycol methyl ether) methacrylate (PEGMA) co-monomers by the RAFT process in a one-pot operation. Target polymers with dopamine phosphonate as side groups and well-defined polymer structures are thus facilely and successfully prepared. Afterwards, a series of polymers with various ratios of dopamine phosphonates as well as the crosslinked polymer analogues are prepared. Benefiting from the dopamine phosphonate side groups, aqueous solutions of those polymers show potential as effective adhesives in both dry and wet conditions, and their adhesive strengths are highly related to ratios of dopamine phosphonates in the polymers. Those polymers are non-cytotoxic and show strong bonding affinities on various substrates including metals, polymers, and bovine bones, suggesting their potential as environmentally friendly general adhesives in broad areas.

中文翻译：

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通过单罐多组分聚合系统轻松制备以贻贝为灵感的聚多巴胺膦酸酯-co-PEGMA。

受贻贝启发的聚合物由于其作为有效粘合剂的潜力而吸引了许多研究兴趣。在这项工作中，通过一锅多组分聚合体系制备了一种新型的贻贝启发性聚合物，聚（多巴胺膦酸酯-co-PEGMA）。多组分聚合体系是指多组分Kabachnik-Fields（KF）反应和可逆加成-断裂链转移（RAFT）聚合体系的组合。通过KF反应将反应物原位转化为多巴胺膦酸酯单体，并通过一锅操作中的RAFT方法将其与聚（乙二醇甲基醚）甲基丙烯酸酯（PEGMA）共聚单体同时聚合。因此，可以轻松而成功地制备出具有多巴胺膦酸酯作为侧基和定义明确的聚合物结构的目标聚合物。然后，制备了一系列具有不同比例的多巴胺膦酸酯的聚合物以及交联的聚合物类似物。得益于多巴胺膦酸酯侧基，那些聚合物的水溶液在干燥和湿润条件下均显示出作为有效粘合剂的潜力，并且它们的粘合强度与聚合物中多巴胺膦酸酯的比例高度相关。这些聚合物是无细胞毒性的，并且在包括金属，聚合物和牛骨在内的各种基材上显示出很强的结合亲和力，表明它们在广泛领域中具有作为环境友好型通用胶粘剂的潜力。这些聚合物的水溶液在干和湿条件下均显示出作为有效粘合剂的潜力，并且它们的粘合强度与聚合物中多巴胺膦酸酯的比例高度相关。这些聚合物是无细胞毒性的，并且在包括金属，聚合物和牛骨在内的各种基材上显示出很强的结合亲和力，表明它们在广泛领域中具有作为环境友好型通用胶粘剂的潜力。这些聚合物的水溶液在干和湿条件下均显示出作为有效粘合剂的潜力，并且它们的粘合强度与聚合物中多巴胺膦酸酯的比例高度相关。这些聚合物无细胞毒性，并在包括金属，聚合物和牛骨在内的各种基材上显示出很强的键合亲和力，表明它们在广泛领域中具有作为环境友好型通用胶粘剂的潜力。