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Dietary legumes, intestinal microbiota, inflammation and colorectal cancer
Journal of Functional Foods ( IF 5.6 ) Pub Date : 2019-12-19 , DOI: 10.1016/j.jff.2019.103707
Isabel Aranda-Olmedo , Luis A. Rubio

Colorectal cancer is a worldwide disease with major clinical and economic impact, and its occurrence is determined by a variety of factors. In addition to its hereditary component, it is also known to be associated with various inflammatory processes, epigenetic alterations or modifications of the intestinal microbiota. The alimentary habits are crucial in the conformation of gut microbiota. The Mediterranean diet is widely recognized for its health benefits and has been associated with a lower risk of colon cancer. On the other hand, inflammation is a process commonly associated with cancer, and the intestinal microbiota interacts with the host to maintain normal function and health, particularly in processes of immunity and defense. Here, we are focusing in particular on two groups of substances (fibre, protein fractions) present in legumes whose mechanisms of action to prevent colon cancer or inflammation are likely to be mediated by the intestinal microbiota functional composition.



中文翻译:

膳食豆类,肠道菌群,炎症和大肠癌

大肠癌是一种具有重大临床和经济影响的世界性疾病,其发生取决于多种因素。除了其遗传成分外,还已知与肠道菌群的各种炎症过程,表观遗传学改变或修饰有关。饮食习惯对肠道菌群的构型至关重要。地中海饮食因其有益健康而广为人知,并具有降低结肠癌的风险。另一方面,炎症是通常与癌症相关的过程,肠道菌群与宿主相互作用以维持正常功能和健康,特别是在免疫和防御过程中。在这里,我们特别关注两类物质(纤维,

更新日期:2019-12-19
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