In this issue of Cell Chemical Biology, Ko et al. (2019) describe a form of regulated necrosis that depends on active, retrograde transport of vesicles from the plasma membrane to the Golgi. The cell death is distinct from defined modalities including apoptosis, and most tumor lines show enhanced sensitivity to it.

中文翻译：

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逆行运输导致的死亡：避免细胞凋亡。

在本期《细胞化学生物学》中，Ko等人。（2019）描述了一种调节性坏死的形式，其取决于囊泡从质膜向高尔基体的主动逆行转运。细胞死亡与包括细胞凋亡在内的已定义模式不同，大多数肿瘤细胞株显示出对细胞死亡的敏感性增强。