Imported across the plasma membrane by SLC1A5, glutamine has emerged as a metabolic fuel that is catabolized by mitochondrial glutaminase to support tumor growth. The missing link between cytoplasmic and mitochondrial glutamine metabolism is now provided by Yoo et al., identifying the mitochondrial glutamine importer as a variant of SLC1A5.

中文翻译：

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谷氨酰胺将Q跳过线粒体。

谷氨酰胺是通过SLC1A5跨质膜导入的，它是一种代谢燃料，被线粒体谷氨酰胺酶分解代谢以支持肿瘤的生长。Yoo等人现在提供了细胞质和线粒体谷氨酰胺代谢之间缺少的联系，从而将线粒体谷氨酰胺进口商识别为SLC1A5的变体。