Two recent studies reveal a virus anti-defence strategy whereby large, ‘jumbo’ phages protect themselves from both restriction endonucleases and DNA-targeting CRISPR–Cas systems, but not from RNA-targeting ones, by encapsulating the phage genome inside the cell in a ‘nucleus’-like shell that is impenetrable for CRISPR effectors.

中文翻译：

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噬菌体会建立防卫屏障。

最近的两项研究揭示了一种病毒抗防御策略，通过将噬菌体基因组封装在一个细胞内，大型“巨噬细胞”将其自身限制在限制性内切核酸酶和靶向DNA的CRISPR-Cas系统中，而不受靶向RNA的系统的保护。 CRISPR效应子无法穿透的``核''样外壳。