Abstract We aimed to estimate the dietary exposure level of ethoxyquin (EQ) and its main metabolite ethoxyquin dimer (EQDM) in 6 kinds of farmed aquatic animals based on the residues and aquatic animal consumption data from Korea. The residues were measured in 143 aquatic animal samples by LC-MS/MS. The dietary exposure level was estimated under four scenarios based on the WHO guidelines. The residue concentrations of EQ and EQDM were in the ranges of 0.14–24.2 and 0.1–315 μg/kg, respectively. The sum of aquatic animal consumption for six aquatic animals was 6.38 g/day (whole group) and 372 g/day (consumer only) in the national food consumption survey. Based on our results, there is no significant risk resulting from EQ and EQDM exposure of humans under all scenarios. This is the first study to present the residue concentrations and exposure levels of EQ and EQDM in farmed aquatic animals in Korea.

中文翻译：

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韩国养殖水生动物乙氧喹和乙氧喹二聚体的残留和膳食暴露

摘要 我们旨在根据来自韩国的残留和水生动物消费数据，估计 6 种养殖水生动物中乙氧基喹 (EQ) 及其主要代谢物乙氧基喹二聚体 (EQDM) 的膳食暴露水平。通过 LC-MS/MS 测定了 143 个水生动物样品中的残留量。膳食暴露水平是根据世卫组织指南在四种情况下估算的。EQ 和 EQDM 的残留浓度分别在 0.14-24.2 和 0.1-315 μg/kg 的范围内。在全国食品消费调查中，6种水生动物的水生动物消费总量为6.38克/天（整组）和372克/天（仅限消费者）。根据我们的结果，在所有情况下，人类的 EQ 和 EQDM 暴露不会导致显着风险。