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Sertraline in primary care: comments on the PANDA trial - Authors' reply.
The Lancet Psychiatry ( IF 64.3 ) Pub Date : 2020-01-01 , DOI: 10.1016/s2215-0366(19)30480-8
Gemma Lewis 1 , Glyn Lewis 1 ,
Affiliation  

Michael Hengartner and colleagues and Asger Sand Paludan-Müller and Klaus Munkholm suggest that the effects of sertraline on anxiety and general mental health were too small to be of clinical benefit to patients. The figure of 0·77 points quoted by Paludan-Müller and Munkholm is a proportional difference, not a mean difference, and indicates that Generalised Anxiety Disorder Assessment 7-item version (GAD-7) scores were 23% lower at follow-up in those on sertraline compared with placebo.

中文翻译:

舍曲林在初级保健中:对PANDA试验的评论-作者的回复。

Michael Hengartner和同事以及Asger SandPaludan-Müller和Klaus Munkholm指出,舍曲林对焦虑和一般精神健康的影响太小,无法为患者带来临床益处。Paludan-Müller和Munkholm引用的0·77分数字是成比例的差异,而不是均值差异,表明在进行随访时,广义焦虑症评估7项版本(GAD-7)得分降低了23%。舍曲林治疗者与安慰剂治疗者比较。
更新日期:2019-12-19
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