当前位置: X-MOL 学术Biomacromolecules › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Modulating Morphologies and Surface Properties of Nanoparticles from Cellulose-Grafted Bottlebrush Copolymers Using Complementary Hydrogen-Bonding between Nucleobases.
Biomacromolecules ( IF 6.2 ) Pub Date : 2019-12-30 , DOI: 10.1021/acs.biomac.9b01345
Yangyang Yan , Chen Gao , Jianjun Li , Tao Zhang , Guang Yang , Zhongkai Wang , Zan Hua

Herein we report the synthesis of a cellulose-grafted bottlebrush copolymer with nucleobases as hydrophobic moieties. Well-defined spherical micelles from this bottlebrush copolymer were fabricated via a solvent switch method. A morphological transition from spheres to worms was only observed to occur when a diblock copolymer with a complementary nucleobase functionality was introduced. Hydrophobic interaction is not capable of triggering the morphological transformation, and the diblock copolymer with the heterogeneous acrylamide nucleobase monomer can induce the morphological transition at higher A:T molar ratios, which might be caused by the weak H-bonding interaction. This supramolecular "grafting to" method enables the preparation of a series of nanoparticles with similar shapes and dimensions but distinct surface properties such as zeta potentials. Moreover, reversible morphological transitions between worm-like micelles and spheres can be achieved using a reversible collapsing and swelling of a thermoresponsive polymer. This work highlights that a supramolecular "grafting to" approach between complementary nucleobases can be utilized to tune morphologies and surface properties of nanoparticles.

中文翻译:

使用核糖核酸酶之间的互补氢键来调节纤维素接枝的牙刷聚合物的纳米颗粒的形态和表面性能。

在本文中,我们报道了具有核碱基作为疏水性部分的纤维素接枝的牙刷共聚物的合成。通过溶剂转换法,从这种牙刷共聚物中制备出定义明确的球形胶束。仅当引入具有互补核碱基功能的二嵌段共聚物时,才观察到从球形到蠕虫的形态转变。疏水相互作用不能触发形态转变,并且具有异质丙烯酰胺核碱基单体的二嵌段共聚物可以在较高的A:T摩尔比下诱导形态转变,这可能是由弱的H键相互作用引起的。这种超分子的“嫁接” 该方法能够制备一系列具有相似形状和尺寸但具有不同表面性质(例如ζ电势)的纳米粒子。此外,利用热响应性聚合物的可逆塌陷和溶胀,可以在蠕虫状微团和球体之间实现可逆的形态学转变。这项工作强调了互补核碱基之间的超分子“嫁接到”方法可用于调整纳米粒子的形貌和表面特性。
更新日期:2019-12-30
down
wechat
bug