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Factors Associated With Antiretroviral Therapy Reinitiation in Medicaid Recipients With Human Immunodeficiency Virus.
The Journal of Infectious Diseases ( IF 6.4 ) Pub Date : 2020-04-27 , DOI: 10.1093/infdis/jiz666
T Zhang 1 , I B Wilson 1 , B Youn 1 , Y Lee 1 , T I Shireman 1
Affiliation  

BACKGROUND This study was conducted to examine patient characteristics associated with antiretroviral therapy (ART) reinitiation in Medicaid enrollees. METHODS This is a retrospective cohort study that uses Cox proportional hazard regression to examine the association between person-level characteristics and time from ART discontinuation to the subsequent reinitiation within 18 months. RESULTS There were 45 409 patients who discontinued ART, and 44% failed to reinitiate. More outpatient visits (3+ vs 0 outpatient visits: adjusted hazard ratio (adjHR), 1.56; 99% confidence interval [CI], 1.45-1.67) and hospitalization (adjHR, 1.18; 99% CI,1.16-1.20) during follow-up were associated with reinitiation. CONCLUSIONS Failure to reinitiate ART within 18 months was common in this sample. Care engagement was associated with greater ART reinitiation.

中文翻译:

与人类免疫缺陷病毒医疗补助接受者重新开始抗逆转录病毒治疗相关的因素。

背景 进行这项研究是为了检查与医疗补助登记者重新开始抗逆转录病毒疗法 (ART) 相关的患者特征。方法 这是一项回顾性队列研究,使用 Cox 比例风险回归来检查个人水平特征与从 ART 中断到 18 个月内随后重新启动的时间之间的关联。结果 有 45 409 名患者停止了 ART,44% 的患者未能重新启动。更多门诊就诊(3+ vs 0 门诊就诊:调整后风险比 (adjHR),1.56;99% 置信区间 [CI],1.45-1.67)和住院治疗(adjHR,1.18;99% CI,1.16-1.20)起来与重新开始有关。结论 未能在 18 个月内重新启动 ART 在该样本中很常见。护理参与与更好的 ART 重新启动相关。
更新日期:2019-12-17
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