BACKGROUND With advancing age, there is an increase in the time of and number of experiences with psychosocial stressors that may lead to the initiation and/or progression of chronic kidney disease (CKD). Our study tests whether one type of experience, everyday discrimination, predicts kidney function among middle and older adults. METHODS The data were from 10 973 respondents (ages 52-100) in the 2006/2008 Health and Retirement Study, an ongoing biennial nationally representative survey of older adults in the United States. Estimated glomerular filtration rate (eGFR) derives from the Chronic Kidney Disease Epidemiology Collaboration equation. Our indicator of everyday discrimination is drawn from self-reports from respondents. Ordinary Least Squared regression (OLS) models with robust standard errors are applied to test hypotheses regarding the link between everyday discrimination and kidney function. RESULTS Everyday discrimination was associated with poorer kidney function among respondents in our study. Respondents with higher everyday discrimination scores had lower eGFR after adjusting for demographic characteristics (B = -1.35, p < .05), and while attenuated, remained significant (B = -0.79, p < .05) after further adjustments for clinical, health behavior, and socioeconomic covariates. CONCLUSIONS Our study suggests everyday discrimination is independently associated with lower eGFR. These findings highlight the importance of psychosocial factors in predicting insufficiency in kidney function among middle-aged and older adults.

中文翻译：

---

老年人的日常歧视和肾功能：来自健康和退休研究的证据。

背景技术随着年龄的增长，可能导致慢性肾病（CKD）的开始和/或进展的心理社会压力源的经历时间和次数都在增加。我们的研究测试了一种类型的经历，即日常歧视，是否可以预测中老年人的肾功能。方法 数据来自 2006/2008 年健康与退休研究中的 10 973 名受访者（年龄 52-100 岁），该研究是一项针对美国老年人的两年一次的全国代表性调查。估计的肾小球滤过率 (eGFR) 来自慢性肾脏病流行病学协作方程。我们的日常歧视指标来自受访者的自我报告。使用具有稳健标准误差的普通最小二乘回归 (OLS) 模型来检验有关日常歧视与肾功能之间联系的假设。结果 在我们的研究中，日常歧视与受访者的肾功能较差有关。具有较高日常歧视分数的受访者在调整人口特征后具有较低的 eGFR (B = -1.35, p < .05)，虽然有所减弱，但在进一步调整临床、健康后仍显着 (B = -0.79, p < .05)行为和社会经济协变量。结论 我们的研究表明，日常歧视与较低的 eGFR 独立相关。这些发现强调了社会心理因素在预测中老年人肾功能不全方面的重要性。