Under a high-fat diet, the amyloid precursor protein, which is involved in the development of Alzheimer’s disease, accumulates at the protein-entry gate of mitochondria in white adipose tissue, thus leading to mitochondrial dysfunction, adipocyte hypertrophy and obesity.

中文翻译：

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堵塞线粒体蛋白质进入门可促进肥胖。

在高脂饮食下，参与阿尔茨海默氏病发展的淀粉样前体蛋白积聚在白色脂肪组织线粒体的蛋白质进入门中，从而导致线粒体功能障碍，脂肪细胞肥大和肥胖。