AIM The objective of this review was to evaluate the role of diabetes as a risk factor for herpes zoster (HZ) and to discuss implications of prevention by vaccination with available HZ vaccines. METHODS We reviewed studies that investigated the incidence rates of HZ in patients with diabetes. Papers in English or French published between January 2000 and December 2018 have been selected from PubMed and Google Scholarship by using appropriate key words. RESULTS The risk of HZ was significantly higher in patients with diabetes as compared to controls in 11 studies out of 16, although the magnitude of risk associated to diabetes varied across studies from 1.06 to 2.38 (p < 0.05). The incidence of HZ in patients with diabetes increased with age and was higher in women than in men. The incidence of the most common complication of HZ, i.e. post-herpetic neuralgia was also higher in patients with diabetes. CONCLUSIONS The presence of HZ adds supplementary complications to the pre-existing comorbidity in patients with diabetes. Investigating the impact of preventive measure by HZ vaccination is therefore of paramount importance in patients with diabetes.

中文翻译：

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糖尿病是成年人带状疱疹的危险因素：一项综合文献综述。

目的本评价的目的是评估糖尿病作为带状疱疹（HZ）危险因素的作用，并讨论通过接种可用的HZ疫苗进行预防的意义。方法我们回顾了研究糖尿病患者HZ发生率的研究。我们使用适当的关键词从PubMed和Google Scholarship中选择了2000年1月至2018年12月之间以英文或法文发表的论文。结果在16个研究中，有11个研究显示糖尿病患者的HZ风险显着高于对照组，尽管与糖尿病相关的危险程度在1.06至2.38之间变化（p <0.05）。糖尿病患者HZ的发生率随年龄增加而增加，女性高于男性。HZ最常见并发症的发生率，即 糖尿病患者的带状疱疹后神经痛也较高。结论HZ的存在增加了糖尿病患者先前合并症的补充并发症。因此，调查HZ疫苗预防措施的影响在糖尿病患者中至关重要。