The ability to engineer synthetic signaling networks has proven challenging for synthetic biology. A breakthrough design strategy shows that bacterial two-component-system-derived parts can be grafted into mammalian cells to create programmable phosphorylation circuitry.

中文翻译：

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来自细菌部分的哺乳动物信号回路。

工程合成信号网络的能力已被证明对合成生物学具有挑战性。突破性的设计策略表明，细菌两成分系统衍生的部分可以移植到哺乳动物细胞中，以创建可编程的磷酸化电路。