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Association between mean platelet volume in the pathogenesis of type 2 diabetes mellitus and diabetic macrovascular complications in Japanese patients.
Journal of Diabetes Investigation ( IF 3.2 ) Pub Date : 2020-01-13 , DOI: 10.1111/jdi.13198
Hiroyuki Inoue 1, 2 , Mayumi Saito 1 , Kumiko Kouchi 1 , Shun-Ichiro Asahara 3 , Fumihiko Nakamura 1 , Yoshiaki Kido 2, 3
Affiliation  

Mean platelet volume (MPV) is a widely used biological marker of platelet function and activity. Increased MPV is associated with accelerated thrombopoiesis and an elevated risk of cardiovascular disease. However, it is not known whether higher MPV is related to the pathogenesis of type 2 diabetes and diabetic macrovascular complications in Japanese patients. Therefore, we analyzed MPV and its correlation with atherosclerosis in Japanese patients with type 2 diabetes and those who had prediabetes.

中文翻译:

日本患者 2 型糖尿病发病机制中平均血小板体积与糖尿病大血管并发症的相关性。

平均血小板体积 (MPV) 是广泛使用的血小板功能和活性的生物学标志物。MPV 增加与血小板生成加速和心血管疾病风险升高有关。然而,尚不清楚较高的 MPV 是否与日本患者的 2 型糖尿病和糖尿病大血管并发症的发病机制有关。因此,我们分析了日本 2 型糖尿病患者和糖尿病前期患者的 MPV 及其与动脉粥样硬化的相关性。
更新日期:2020-01-13
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