Cyclodextrins (CDs) had been regarded as destructors in molecular assembly systems for a long time until CD/surfactants were found to assemble into high order structure driven by hydrogen bonding between CDs. Thereafter, intensive researches have been conducted on construction and regulation of CD/amphiphile systems. Here, we summarized the recent progress on construction and regulation of cyclodextrins and amphiphiles assembly. The scope of amphiphiles have been extended from surfactants (ionic surfactants, zwitterion surfactants, non-ionic surfactants, gemini surfactant, etc.), to non-typical amphiphiles (amines, aromatic molecules, alkanes, etc.). Owing to the abundant choices of guest amphiphiles and dynamic nature of host-guest inclusive interaction, numerous regulation methods (such as enzyme, light, pH, concentration, temperature, etc.) have been employed in CD/amphiphile systems. Moreover, remarks and future perspectives are also discussed at the end of this review, which is expected to stimulate progress on both mechanism and application level.

长期以来，环糊精（CD）在分子组装系统中一直被视为破坏者，直到发现CD /表面活性剂被CD之间的氢键驱动组装成高阶结构。此后，已经对CD /两亲体系的构建和调控进行了深入研究。在这里，我们总结了环糊精和两亲分子组装的构建和调控的最新进展。两亲物的范围已从表面活性剂（离子表面活性剂，两性离子表面活性剂，非离子表面活性剂，双子表面活性剂等）扩展到非典型两亲物（胺，芳族分子，烷烃等）。由于来宾两亲物的选择丰富以及宿主-客体包容性相互作用的动态性质，因此有许多调节方法（例如酶，光，pH，浓度，温度等）。）已用于CD /两亲系统中。此外，在本评论的结尾还讨论了言论和未来观点，这有望在机制和应用水平上促进进步。