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Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A.
Beilstein Journal of Organic Chemistry ( IF 2.7 ) Pub Date : 2019-12-12 , DOI: 10.3762/bjoc.15.291
Qiao Li 1 , Chen Zhuang 1 , Donghua Wang 1 , Wei Zhang 1 , Rongxuan Jia 1 , Fengxia Sun 2 , Yilin Zhang 3 , Yunfei Du 1
Affiliation  

The construction of the biologically interesting chromone skeleton was realized by PhIO-mediated dehydrogenation of chromanones under mild conditions. Interestingly, this method also found application in the synthesis of the naturally occurring frutinone A.

中文翻译:

通过PhIO介导的脱氢法构建带有吸电子基团的三取代色酮骨架及其在合成果丁酮A中的应用。

通过PhIO介导的色酮在温和条件下的脱氢作用,实现了具有生物学意义的色酮骨架的构建。有趣的是,该方法还发现了在天然存在的果丁酮A合成中的应用。
更新日期:2019-12-13
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