A multiphase second‐order moment turbulent model was developed including an improved closure Reynolds stress transport to describe effectively the anisotropic characteristics of bubble‐liquid turbulent flow. The two‐phase hydrodynamics in a bubble column were numerically simulated by an in‐house code. The effect of the amount of jetting holes on bubble‐liquid hydrodynamics in relationship with a cell culture was investigated. Firstly, the bubble energy production correlation was proposed to verify the higher cell damage rate near gas inlet regions. The larger amounts of jetting holes resulted in an increase of bubble stress, bubble kinetic energy, and energy dissipation, particularly bubble energy production at the near gas inlet, which boosted cell damage.

中文翻译：

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鼓泡孔对鼓泡塔气液流体动力学的影响

建立了多相二阶矩湍流模型，其中包括改进的闭合雷诺应力传递，以有效描述气泡-液体湍流的各向异性特征。气泡塔中的两相流体动力学通过内部代码进行了数值模拟。研究了与细胞培养有关的射孔数量对气泡-液体流体动力学的影响。首先，提出了气泡能量产生的相关性，以验证气体入口区域附近较高的细胞损伤率。大量的喷射孔导致气泡应力，气泡动能和能量耗散的增加，特别是在近气体入口处产生的气泡能量的增加，这加剧了细胞的损伤。