The phytochemical, antioxidants and antimicrobial potential of aqueous and methanol fruit extracts of Nauclea latifolia (African peach) and its application in biosynthesis of silver nanoparticles and its cold cream formulations were investigated.

The phytochemical constituents, antioxidant and antimicrobial potential of aqueous and methanolic fruit extract of N. latifolia were investigated. The extracts were used in bio-reduction of silver nitrate to nanoparticles. Formation of nanoparticles was confirmed and characterized by UV-Vis spectrophotometer. FTIR, Energy dispersive X-Ray and Scanning Electron microscopy. The nanoparticles were used in cream formulation and the antimicrobial properties of the nanoparticles and formulated creams were evaluated using agar well diffusion method.

The phytochemical evaluation of Nauclea latifolia crude extracts showed the presence of alkaloids, flavonoids, saponins, terpenoids, anthraquinones and steroids, tannins and glycosides. N. Latifolia methanol fruit extract exhibited antioxidant activity in a dose dependent manner. The Surface Plasmon Resonance peak was 350 nm and functional group such as hydroxyl, carboxyl, alkyl halides, phenols, amines, carbonyl and amide groups were present which was important for the bio-reduction and capping of the silver ions into nanoparticles. EDX analysis showed silver as the main element present and the nanoparticles were irregular in shape and 12 nm in size. The formulated creams were stable, cosmetically appealing with satisfactory pH, viscosity and spreadability.

The Nauclea latifolia aqueous extract-silver nanoparticles and its cream formulation exhibited potent antimicrobial and antioxidant activities. This work reports a simple, eco-friendly, and economic means to synthesis of AgNPs using aqueous extract of Nauclea latifolia (African peach).

研究了非洲水仙（Nauclea latifolia）（非洲桃）的水和甲醇果实提取物的植物化学，抗氧化剂和抗菌潜力及其在银纳米颗粒及其冷霜配方的生物合成中的应用。

研究了阔叶猪笼草水和甲醇果实提取物的植物化学成分，抗氧化剂和抗菌潜力。提取物用于将硝酸银生物还原为纳米颗粒。通过UV-Vis分光光度计确认并表征了纳米颗粒的形成。FTIR，能量色散X射线和扫描电子显微镜。将纳米颗粒用于乳膏制剂中，并使用琼脂井扩散法评估纳米颗粒和乳膏剂的抗菌性能。

uc子粗提物的植物化学评价表明存在生物碱，类黄酮，皂角苷，萜类化合物，蒽醌和类固醇，单宁和糖苷。N. Latifolia甲醇水果提取物以剂量依赖性方式表现出抗氧化活性。表面等离子体共振峰为350nm，并且存在官能团如羟基，羧基，卤代烷，酚，胺，羰基和酰胺基，这对于生物还原和将银离子封端到纳米颗粒中是重要的。EDX分析显示存在银作为主要元素，并且纳米颗粒形状不规则且尺寸为12nm。所配制的乳膏是稳定的，具有令人满意的pH值，粘度和铺展性的化妆品吸引力。

的乌檀latifolia的水性提取物的银纳米颗粒和其乳膏制剂表现出有效的抗微生物和抗氧化活性。这项工作报告了一种简单的，生态友好的，经济的方法，可以使用Nauclea latifolia（非洲桃）的水提物来合成AgNP 。