A series of hetero ligand MLB complexes (1–5) were synthesised from tridentate NO₂ type Schiff base [H₂L: (E)-2-((2-hydroxy-4-methoxyphenyl)(phenyl)methyleneamino)benzoic acid; derived from 2-hydroxy-4-methoxybenzophenone and 2-aminobenzoic acid] and bidentate N₂ type 1,10-phenanthroline (B: phen) ligands. The structural characterization of the synthesised MLB complexes were carried out via analytical as well as various spectral studies. Additionally, the low molar conductance values (Λ_m = 14–22 Ω⁻¹ cm² mol⁻¹) imply that the complexes (1–5) are non-electrolytes. The obtained results reinforce that stoichiometry of the mononuclear hetero ligand complexes can be represented as [M(II)-Schiff base(L)-phen(B)·H₂O] and both H₂L and (B) ligands can act as tri and bidentates respectively. Moreover, both the ligands bind with metal(II) ions to build a stable six, six, five membered chelate rings with octahedral geometry. The existing solvent water molecule is confirmed from thermal as well as vibrational analysis. Their microcrystalline nature and uniform surface morphology were confirmed by both powder XRD and SEM studies. 3D molecular modeling and analysis of NiLB and CuLB complexes (3 and 4) were also studied. Mn(II), Ni(II) and Cu(II) complexes (1, 3 and 4) strongly interact with DNA through intercalation binding with strong binding constant values. The obtained K_app values were 5.23, 4.98, 6.36, 7.21 and 4.86 × 10⁵ mol⁻¹ for MLB complexes (1–5) respectively and the negative Δ^‡G values shown that all the complexes are strongly interact with DNA in a spontaneous manner. Further, remarkable biological, antioxidant and DNA activities were remarkably exhibited by MnLB, NiLB and CuLB complexes.

一系列的杂配体配合物MLB的（1 - 5）购自三齿NO合成₂型席夫碱[ ħ ₂大号：（ë）-2 - （（2-羟基-4-甲氧基苯基）（苯基）亚甲基氨基）苯甲酸; 衍生自2-羟基-4-甲氧基二苯甲酮和2-氨基苯甲酸]和二齿N ₂型1,10-菲咯啉（B：phen）配体。合成的MLB配合物的结构表征是通过分析以及各种光谱研究进行的。另外，所述低摩尔电导值（Λ_米 = 14-22Ω ^-1 厘米² 摩尔^-1）意味着复合物（1 - 5）是非电解质。获得的结果加强了单核杂配体配合物的化学计量可以表示为[M（II）-席夫碱（L）-phen（B）·H ₂ O]，H ₂ L和（B）配体都可以充当三和双齿。此外，两个配体均与金属离子结合形成具有八面体几何形状的稳定的六，六，五元螯合环。现有的溶剂水分子已通过热分析和振动分析得到确认。通过粉末XRD和SEM研究证实了它们的微晶性质和均匀的表面形态。NiLB和CuLB配合物的3D分子建模和分析（3和4）也进行了研究。锰（II），镍（II）和Cu（II）配合物（1，3和4）强烈地与DNA相互作用通过插层具有很强的结合常数结合值。将所得到的ķ_应用值分别为5.23，4.98，6.36，7.21和4.86×10 ⁵ 摩尔^-1为MLB复合物（1 - 5）分别与负Δ ^‡所示的G值，所有的配合物是强烈的相互作用与DNA以自发方式。此外，MnLB，NiLB和CuLB配合物具有显着的生物学，抗氧化剂和DNA活性。