This paper describes a miniaturized multisensor platform (MP-ISES) consisting of electrodes: a reference one (RE) and ion-selective electrodes (ISEs) for monitoring Na⁺, K⁺, Ca²⁺, Mg²⁺, Cl⁻, and SCN⁻ ions and pH in human saliva. Gold electrode surface was modified by deposition of two layers: electrosynthesized PEDOT:PSS forming an intermediate layer, and ion-selective membrane. The developed ISEs were characterized by a wide linear range and sensitivity consistent with the Nernst model. The entire MP-ISEs are characterized by satisfactory metrological parameters demonstrating their applicability in biomedical research, in particular in measurements concerning determination of ionic profiles of saliva. Saliva samples of 18 volunteers aged from 20 to 26 participating in a month experiment had been daily collected and investigated using the MP-ISEs assigned individually to each person. Personalized profiles of ions (ionograms) in saliva, such as Na⁺, K⁺, Ca²⁺, Mg²⁺, Cl⁻, SCN⁻, and H⁺, were obtained.

本文描述了一种小型化的多传感器平台（MP-ISES）组成的电极：一个参考（RE）和离子选择性电极（离子选择电极），用于监控的Na ⁺，K ⁺，钙²⁺，镁²⁺，氯^{- ，}和SCN ^-离子和pH值在人唾液。通过沉积两层来修饰金电极的表面：形成中间层的电合成PEDOT：PSS和离子选择膜。发达的ISE具有与Nernst模型一致的宽线性范围和灵敏度。整个MP-ISE的特点是具有令人满意的计量参数，这证明了它们在生物医学研究中的适用性，特别是在涉及唾液离子谱测定的测量中。每天收集18个年龄在20至26岁的志愿者进行每月实验的唾液样本，并使用分别分配给每个人的MP-ISE进行调查。在唾液离子（电离图）的个性化的简档，如Na ⁺，K ⁺，钙²⁺，镁²⁺，氯^-，SCN ^- ，和H ⁺，获得。