Abstract Antifouling/antibacterial coating derived from a sustainable natural resource for biomedical devices have shown promising outcomes, especially in the prevention of bacterial growth. Herein, pulse-plasma chemical vapour deposition is used to fabricate antimicrobial coatings from Terpinen-4-ol, a tea tree oil-based precursor. In this manuscript, during RF plasma polymerisation, pulsed plasma is used to retain the pristine monomer structure in the developed stable coating and thereby enhance its antibacterial activity. The developed films have tunable physical and chemical properties. Diverse film surface properties were obtained by varying the plasma deposition parameters, mainly the deposition mode (pulse and continuous wave) and duty cycle. The role of film wettability on degree of bacterial attachment has been elucidated. Overall, the number of viable bacteria on all the deposited coatings (25–30%) were reduced to half with respect to the control (56%). Graphic Abstract

中文翻译：

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Terpinen-4-ol 的脉冲等离子体沉积：对聚合机制的洞察和已开发薄膜的增强抗菌反应

摘要 源自生物医学设备可持续自然资源的防污/抗菌涂层已显示出可喜的成果，尤其是在防止细菌生长方面。在本文中，脉冲等离子体化学气相沉积用于从茶树油基前体 Terpinen-4-ol 制造抗菌涂层。在这份手稿中，在 RF 等离子体聚合过程中，脉冲等离子体用于在开发的稳定涂层中保留原始单体结构，从而增强其抗菌活性。开发的薄膜具有可调的物理和化学特性。通过改变等离子体沉积参数，主要是沉积模式（脉冲和连续波）和占空比，可以获得不同的薄膜表面特性。薄膜润湿性对细菌附着程度的作用已经阐明。全面的，所有沉积涂层上的活细菌数量 (25-30%) 相对于对照 (56%) 减少了一半。图形摘要