Magnetic resonance imaging (MRI) is a well-established modality for assessing renal morphology and function, as well as changes that occur during disease. However, the significant metabolic changes associated with renal disease are more challenging to assess with MRI. Hyperpolarized carbon-13 MRI is an emerging technique which provides an opportunity to probe metabolic alterations at high sensitivity by providing an increase in the signal-to-noise ratio of 20,000-fold or more. This review will highlight the current status of hyperpolarised 13C-MRI and its translation into the clinic and how it compares to metabolic measurements provided by competing technologies such as positron emission tomography (PET).

中文翻译：

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超极化的13C-MRI代谢和功能成像：一种新兴的肾脏MR诊断方法。

磁共振成像（MRI）是一种行之有效的方法，用于评估肾脏的形态和功能以及疾病期间发生的变化。但是，与肾脏疾病相关的显着代谢变化对于用MRI进行评估更具挑战性。超极化碳13 MRI是一种新兴技术，可通过增加20,000倍或更多的信噪比，提供机会以高灵敏度探测代谢变化。这篇综述将着重介绍超极化13C-MRI的现状及其在临床中的应用，以及它如何与竞争技术（如正电子发射断层扫描（PET））提供的代谢测量结果进行比较。