This review focuses on the production of natural bioactive products and their biocontrol capabilities of the enterobacterial genus Serratia. Serratia represents a unique group of enterobacteria with a notable secondary metabolism, able to produce a wide range of natural bioactive products including the β-lactam antibiotic carbapenem or the antifungal compound oocydin A. However, until very recently, most of the Serratia isolates originated from human and animal infections, and a systematic approach to the isolation of Serratia from natural habitats has been missing. The paucity of environmental isolates has so far limited our understanding of the potential of Serratia to produce new natural bioactive products and their capacity to be used in sustainable agriculture as biocontrol agents. The ability to isolate Serratia from soils, together with the analytical capabilities afforded by the democratization of genome sequencing methodologies, opens the door to the isolation and characterization of such novel biocontrol agents, hitherto inaccessible.

这篇综述着重于天然生物活性产品的生产及其对肠杆菌沙雷氏菌（Serratia）的生物控制能力。沙雷氏菌代表具有独特的次级代谢的肠杆菌群，能够产生多种天然生物活性产物，包括β-内酰胺类抗生素碳青霉烯或抗真菌化合物oocydinA。但是，直到最近，大多数沙雷氏菌分离株都起源于人类和动物的感染，以及从自然栖息地中分离沙雷氏菌的系统方法都缺失了。迄今为止，由于缺乏环境隔离株，我们对沙雷氏菌潜力的了解受到限制。生产新的天然生物活性产品及其在可持续农业中用作生物防治剂的能力。从土壤中分离沙雷氏菌的能力，以及由基因组测序方法的民主化提供的分析能力，为迄今无法获得的这种新型生物防治剂的分离和表征打开了大门。