The hippocampus comprises two neural signals-place cells and θ oscillations-that contribute to facets of spatial navigation. Although their complementary relationship has been well established in rodents, their respective contributions in the primate brain during free navigation remains unclear. Here, we recorded neural activity in the hippocampus of freely moving marmosets as they naturally explored a spatial environment to more explicitly investigate this issue. We report place cells in marmoset hippocampus during free navigation that exhibit remarkable parallels to analogous neurons in other mammalian species. Although θ oscillations were prevalent in the marmoset hippocampus, the patterns of activity were notably different than in other taxa. This local field potential oscillation occurred in short bouts (approximately .4 s)-rather than continuously-and was neither significantly modulated by locomotion nor consistently coupled to place-cell activity. These findings suggest that the relationship between place-cell activity and θ oscillations in primate hippocampus during free navigation differs substantially from rodents and paint an intriguing comparative picture regarding the neural basis of spatial navigation across mammals.

中文翻译：

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自由导航期间灵长类海马体的空间编码。

海马包含两个神经信号-放置细胞和θ振荡-有助于空间导航的各个方面。尽管它们在啮齿动物中的互补关系已经很好地建立了，但是在自由航行期间它们在灵长类动物大脑中的各自贡献仍然不清楚。在这里，我们记录了自由移动的mos猴在自然探索空间环境以更明确地调查此问题时海马中的神经活动。我们报告mar猴在自由导航期间海马的地方细胞，表现出与其他哺乳动物物种中类似神经元的显着相似之处。尽管猴海马区普遍存在θ振荡，但其活动模式与其他类群明显不同。这种局部场电势振荡发生在短暂的回合中（大约）。4 s）-而不是连续-既没有受到运动的显着调节，也没有持续地与位置细胞活动耦合。这些发现表明，在自由航行期间，灵长类海马中的位置细胞活性与θ振荡之间的关系与啮齿动物有很大的不同，并且描绘了关于跨哺乳动物空间航行的神经基础的有趣的比较图景。