The spinning mesh disc reactor (SMDR) is a rotating catalytic reactor with a potential to facilitate process intensification. In this study, the scale-up of a newly designed SMDR has been demonstrated by increasing (i) cloth size and (ii) cloth number for tributyrin hydrolysis and nitroaldol condensation reaction. The effect of spinning speed, cloth size and cloth number was investigated using design of experiments and the results show an increase in the cloth size or cloth number leads to a higher reaction rate. This is due to (i) an increased catalyst loading with increase in surface area and volume of the cloth stack and (ii) reduced film thickness with increasing shear forces and longer residence times improving the overall mass transfer. Addition of multiple cloths of increasing cloth sizes further improved the reaction rates at higher substrate concentration. A maximum reaction rate of 6.9 mM min⁻¹ and 0.043 mmol min^-1 was obtained for three 50 cm cloths for tributyrin hydrolysis and nitroaldol condensation reaction respectively. These results highlight the potential routes for the SMDR scale-up without a loss in the reaction efficiency for a range of catalytic reactions, thus allowing for a tuneable operation of the SMDR for industrial applications.

旋转筛网盘式反应器（SMDR）是一种旋转催化反应器，具有促进工艺强化的潜力。在这项研究中，通过增加（i）布料尺寸和（ii）甘油三丁酸酯水解和硝基醛缩合反应的布料数量，证明了新设计的SMDR的规模扩大。使用实验设计研究了纺丝速度，布号和布号的影响，结果表明，布号或布号的增加导致更高的反应速率。这是由于（i）催化剂负载增加，布叠的表面积和体积增加，以及（ii）膜厚度减小，剪切力增加，停留时间延长，从而改善了整体传质。添加增加布号的多个布进一步提高了在较高底物浓度下的反应速率。最大反应速率为6.9 mM min对于三块50cm的布分别用于三丁酸甘油酯水解和硝基醛缩合反应，获得了^-1和0.043mmol min ^-1。这些结果突显了SMDR扩大规模的潜在途径，而不会损失一系列催化反应的反应效率，从而使SMDR在工业应用中可调节运行。