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Bioaccessibility and catabolism of phenolic compounds from jaboticaba (Myrciaria trunciflora) fruit peel during in vitro gastrointestinal digestion and colonic fermentation
Journal of Functional Foods ( IF 5.6 ) Pub Date : 2019-12-10 , DOI: 10.1016/j.jff.2019.103714
Andréia Quatrin , Cristine Rampelotto , Roberson Pauletto , Luana Haselein Maurer , Sabrina Marafiga Nichelle , Bruna Klein , Renata Fritzsche Rodrigues , Mário Roberto Maróstica Junior , Bruna de Souza Fonseca , Cristiano Ragagnin de Menezes , Renius de Oliveira Mello , Eliseu Rodrigues , Vivian Caetano Bochi , Tatiana Emanuelli

Jaboticaba peel powder (JPP) digestion was investigated for the first time using an in vitro static model of gastrointestinal digestion associated with a colonic fermentation assay with human feces to elucidate the catabolism and bioaccessibility of fruit polyphenols. Anthocyanins had low bioaccessibility (0.08–2.3%). Most hydrolyzable tannins (1.2–166.0%) and flavonols (0–36.8%) had greater bioaccessibility than anthocyanins. Despite their low bioaccessibility (0.08–2.3%), anthocyanins were the most abundant polyphenols in JPP and in the bioaccessible intestinal fraction followed by hydrolyzable tannins. There was fast degradation of anthocyanins and progressive catabolism of hydrolyzable tannins during the colonic fermentation assay. Urolithins and protocatechuic acid were the major catabolites found; their increase was parallel to the decrease of pathogenic bacteria counts and increase of short-chain fatty acids and gas production. JPP digestion yields bioactive polyphenol catabolites that may act as antioxidants and, with JPP dietary fiber, improve gut microbiota metabolism.



中文翻译:

生物有效性和从嘉宝果酚类化合物的分解代谢(Myrciaria trunciflora)期间果皮体外胃肠消化和结肠发酵

首次使用体外方法研究了Jaboticaba果皮粉(JPP)的消化胃肠消化的静态模型与人类粪便的结肠发酵试验相关联,以阐明水果多酚的分解代谢和生物可及性。花青素的生物利用度低(0.08–2.3%)。大多数可水解单宁(1.2–166.0%)和黄酮醇(0–36.8%)比花青素具有更高的生物利用度。尽管它们的生物利用度较低(0.08–2.3%),但在JPP中以及在生物可利用的肠道成分中,花青素是最丰富的多酚,其次是可水解的丹宁酸。在结肠发酵试验中,花色苷快速降解,可水解单宁逐渐分解代谢。尿石素和原儿茶酸是发现的主要分解代谢产物。它们的增加与致病菌数量的减少以及短链脂肪酸和气体产量的增加平行。

更新日期:2019-12-11
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