The relationship between long working hours and body weight outcomes remains inconclusive; thus, we conducted a meta‐analysis to assess the effect of long working hours on weight‐related outcomes. PubMed and Embase databases were searched from their inception to June 2019. A random‐effects model was used to assess the pooled odds ratio (OR) and corresponding confidence interval (CI). Subgroup analyses and sensitivity analyses were conducted to explore sources of heterogeneity. Publication bias was evaluated by the Begg's and Egger's tests. A total of 29 articles involving 374 863 participants were included. The pooled OR of long working hours on weight‐related outcomes was 1.13 (95% CI, 1.07‐1.19). In subgroup analysis stratified by definition of outcomes, the pooled ORs of long working hours on “weight gain/BMI increase,” “BMI ≥ 25 kg/m²,” and “BMI ≥ 30 kg/m²” were 1.19 (95% CI, 1.02‐1.40), 1.07 (95% CI, 1.00‐1.14), and 1.23 (95% CI, 1.09‐1.39), respectively. We found evidence of publication bias, but correction for this bias using the trim‐and‐fill method did not alter the combined OR substantially. There was evidence to suggest that long working hours are associated with adverse weight‐related outcomes. Preventative interventions such as improved flexibility and healthy working schedules should be established for employees.

中文翻译：

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长时间工作与体重相关的结果相关吗？对观察性研究的荟萃分析。

长时间工作与体重结局之间的关系尚无定论；因此，我们进行了荟萃分析，以评估长时间工作对体重相关结局的影响。从成立到2019年6月，对PubMed和Embase数据库进行了搜索。使用随机效应模型评估合并的优势比（OR）和相应的置信区间（CI）。进行了亚组分析和敏感性分析，以探索异质性的来源。出版偏倚通过Begg's和Egger's检验进行评估。共纳入29篇文章，涉及374863名参与者。与体重有关的结果，长时间工作的总OR为1.13（95％CI，1.07-1.19）。在按结果定义分层的亚组分析中，长时间工作的“ OR”（体重增加/ BMI增加），“ BMI≥25 kg / m”汇总为OR² ”和“ BMI≥30 kg / m ² ”分别为1.19（95％CI，1.02-1.40），1.07（95％CI，1.00-1.14）和1.23（95％CI，1.09-1.39）。我们发现了发表偏倚的证据，但是使用修整和填充方法对该偏倚进行校正并没有实质性地改变合并后的OR。有证据表明，长时间工作与不良的体重相关结果有关。应该为员工建立诸如提高灵活性和健康的工作时间表之类的预防性干预措施。