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Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report.
Journal of Medical Case Reports Pub Date : 2019-12-07 , DOI: 10.1186/s13256-019-2290-6
Fousséni Alassani 1 , Panawe Kassang 2 , Efoe-Ga Amouzou 3 , Boyodi Tchangai 1 , Kossi Abossisso Sakiye 4 , Tchin Darré 5 , Bayaki Saka 2 , Komla Attipou 1
Affiliation  

INTRODUCTION Pyoderma gangrenosum is a rare, idiopathic, inflammatory, neutrophilic dermatitis characterized by sterile skin ulceration. It can be associated with an underlying pathology, especially inflammatory bowel disease and hematological malignancies. Its association with a malignant pathology in the context of a paraneoplastic syndrome is more commonly described in hematological malignancies, with solid tumors being rare. CASE REPORT We report a case of a 39-year-old West African man with pyoderma gangrenosum that developed 6 months before the clinical expression of rectosigmoid junction cancer. The removal of the cancer resulted in the patient's recovery. CONCLUSION Recurrent pyoderma gangrenosum lesions may be the expression of colonic adenocarcinoma in paraneoplastic syndrome and require colonoscopy, especially in at-risk patients.

中文翻译:

副肿瘤性坏疽性脓疱病与直肠乙状结肠连接处的腺癌相关:一例病例报告。

简介坏疽性脓皮病是一种罕见的,特发性,炎症性,嗜中性粒细胞性皮炎,其特征是无菌性皮肤溃疡。它可能与潜在的病理学有关,尤其是炎症性肠病和血液系统恶性肿瘤。在副肿瘤综合征的背景下,它与恶性病理的关联在血液系统恶性肿瘤中更为常见,实体瘤很少见。病例报告我们报告了一例39岁的西非男性,患有坏疽性脓皮病,在直肠乙状结肠连接癌的临床表达前六个月发展。癌症的去除导致患者的康复。结论复发性脓皮病性坏死病可能是副肿瘤综合征中结肠腺癌的表达,需要结肠镜检查,特别是在高危患者中。
更新日期:2019-12-07
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