PURPOSE Many people experience aging-related losses in different physical domains, which leads to a condition often called physical frailty (PF). The aim of this study was to analyse the effects of two different, 28-weeks, class chair-exercise protocols on salivary steroid hormones (SH), PF, and functional disabilities (FD) in frail older women. METHODS A sample of older frail individuals (n = 60, 817.84 years) participated in the study and were divided into three groups: chair elastic-band muscle strength exercises (CSE), n = 20), chair-multimodal exercise (CME, n = 21) and a control non-exercise group (CGne, n = 19). Both exercise programs consisted of 45 min of supervised chair-based exercise group classes, carried out 3 times/week. CME participants performed a progressive training using walking, mobility and body weight resistance exercises. The CSE participants exercised using an elastic-band system of progressive exercises. Both CSE and CME followed a circuit training protocol. The controls did not change their usual lifestyle. The indicators of PF, FD and SH concentrations were analyzed before and after the intervention. RESULTS Both exercise programs diminished the PF status showing significant time and time versus treatment interactions (p < .01). An increase in the CME group, between baseline and 14-weeks, and in the CSE group, after 28 weeks, for Testosterone concentrations was observed (p < .01). Dehydroepiandrosterone (DHEA) increased after 28-weeks in the CME group and decreased in the CGne after the same period (p < .05). Both exercise programs decreased the negative scores of several FD domains, specially fear of falling that showed significant effects with time (p < .01), and time vs intervention (p < .05). CONCLUSION Both chair-exercise based programs were effective in stimulating positive changes in physical health and in steroid hormone responses, especially in DHEA. The control group did show a negative trend towards an increased PF status and decreased levels of SH. It is crucial for public health to identify the main factors associated with Functional Disability and Physical Frailty that underlie the development of new methods for complementary therapies, such as the use of low doses of hormonal supplementation combined with long-term exercise interventions.

中文翻译：

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在制度化的老年妇女中进行的基于椅子的运动计划：唾液类固醇激素，残疾和虚弱变化。

目的许多人在不同的物理领域都遭受与衰老相关的损失，这导致了通常被称为身体虚弱（PF）的疾病。这项研究的目的是分析体弱的老年妇女两种不同的28周的课堂锻炼方式对唾液类固醇激素（SH），PF和功能障碍（FD）的影响。方法一组年龄较弱的个体（n = 60，817.84岁）参加了研究，分为三组：椅子弹性带肌肉力量练习（CSE），n = 20；椅子多模态锻炼（CME，n）。 = 21）和对照组非运动组（CGne，n = 19）。两种运动方案均由45分钟的有监督的基于椅子的运动组课程组成，每周进行3次。CME参与者使用步行，移动性和体重抵抗运动进行了渐进式训练。CSE参与者使用渐进式练习的松紧带系统进行练习。CSE和CME都遵循电路训练协议。控件并没有改变他们通常的生活方式。干预前后分析PF，FD和SH浓度的指标。结果两种运动方案均降低了PF状态，显示了显着的时间和时间对治疗相互作用的影响（p <.01）。CME组在基线至14周之间以及睾丸激素浓度在28周后有所增加（p <0.01）。CME组在28周后脱氢表雄酮（DHEA）升高，而在同一时期后CGne降低（p <.05）。两种运动程序都降低了多个FD域的负面评分，特别是对跌倒的恐惧会随着时间的推移而显示出显着的影响（p <.01），而时间对干预的影响（p <.05）。结论两种基于椅子运动的程序均能有效刺激身体健康和类固醇激素反应（尤其是DHEA）中的积极变化。对照组确实显示出不良的趋势，即PF状态增加和SH水平降低。识别与功能障碍和身体虚弱相关的主要因素对于公共卫生至关重要，这些因素是开发补充疗法的新方法的基础，例如使用低剂量的激素补充剂和长期运动干预措施。结论两种基于椅子运动的程序均能有效刺激身体健康和类固醇激素反应（尤其是DHEA）中的积极变化。对照组确实显示出不良的趋势，即PF状态增加和SH水平降低。识别与功能障碍和身体虚弱相关的主要因素对于公共卫生至关重要，这些因素是开发补充疗法的新方法的基础，例如使用低剂量的激素补充剂和长期运动干预措施。结论两种基于椅子运动的程序均能有效刺激身体健康和类固醇激素反应（尤其是DHEA）中的积极变化。对照组确实显示出不良的趋势，即PF状态增加和SH水平降低。识别与功能障碍和身体虚弱相关的主要因素对于公共卫生至关重要，这些因素是开发补充疗法的新方法的基础，例如使用低剂量的激素补充剂和长期运动干预措施。