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Gut microbiota - host interactions now also brain-immune axis.
Current Opinion in Neurobiology ( IF 5.7 ) Pub Date : 2019-12-06 , DOI: 10.1016/j.conb.2019.10.009
Haitham Hajjo 1 , Naama Geva-Zatorsky 2
Affiliation  

The 'gut-brain axis' is a fairly new term in the fairly new field of the gut microbiota. The gut microbiota, the collection of microorganisms residing in intestines of vertebrates, was shown to have major effects on host physiology. The field has seen a renaissance due to advances in deep-sequencing. Recently, there is an explosion of studies on the physiological and therapeutic potential of the gut microbiota. These microbes are considered to reside in symbiosis with their hosts, and are termed 'commensals', originated from Latin - 'at table together'. We provide the gut microbes nutrients and a living niche, and they in turn, provide us with essentially the same - nutrients derived from the food we eat, that we cannot digest, and essential functions for health and longevity. In the past few years it has been appreciated that gut microbes can even affect our brain, behavior, and neurological disorders, which we here review.

中文翻译:

肠道菌群-宿主之间的相互作用现在也可以是脑免疫轴。

在肠道菌群的新领域中,“肠脑轴”是一个相当新的术语。肠道微生物群(居住在脊椎动物肠道中的微生物的集合)显示出对宿主生理的重要影响。由于深度测序技术的进步,该领域已经复兴。最近,关于肠道菌群的生理和治疗潜力的研究激增。这些微生物被认为与它们的宿主共生,被称为“共生”,起源于拉丁语-“一起吃饭”。我们为肠道微生物提供营养和活生生的生态位,而它们反过来又为我们提供了与我们相同的营养-来自我们食用的食物的营养,我们无法消化,以及对健康和长寿的基本功能。
更新日期:2019-12-06
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