Neurotransmitters (NTs) are chemical messengers in the synaptic transmission process. NTs play important roles in human activities, and imbalanced NTs levels in the body lead to severe diseases such as Alzheimer’s and Parkinson’s diseases. The accurate diagnosis of NTs imbalances has been identified only after patient death through identifying plaques in the brain. Hence, the diagnosis and monitoring of NTs concentrations is important for avoiding serious illnesses. Many researchers have explored the use of robust diagnostic tools with various nanomaterials and techniques. Herein, we investigated the mechanism of reactions between NTs and nanomaterials, the role of nanomaterials in diagnostic tools and the different techniques used in the accurate detection of NTs. Furthermore, we discussed the simultaneous detection of NTs in a single sensing channel, detection in biological samples and future perspectives for nanomaterials in NTs detection.

神经递质（NTs）在突触传递过程中是化学信使。NTs在人类活动中起着重要作用，并且体内NTs水平的失衡会导致严重的疾病，例如老年痴呆症和帕金森氏病。仅在患者死亡后才通过鉴定大脑斑块来鉴定NTs失衡的准确诊断。因此，NTs浓度的诊断和监测对于避免严重疾病很重要。许多研究人员已经探索了将健壮的诊断工具与各种纳米材料和技术结合使用的方法。在本文中，我们研究了NT与纳米材料之间的反应机理，纳米材料在诊断工具中的作用以及用于精确检测NT的不同技术。此外，