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Human Milk Oligosaccharides Differently Modulate Goblet Cells Under Homeostatic, Proinflammatory Conditions and ER Stress.
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2019-12-11 , DOI: 10.1002/mnfr.201900976
Lianghui Cheng 1 , Chunli Kong 1 , Marthe T C Walvoort 2 , Marijke M Faas 1 , Paul de Vos 1
Affiliation  

Human milk oligosaccharides (hMOs) have beneficial effects on intestinal barrier function, but the mechanisms of action are not well understood. Here, the effects of hMOs on goblet cells, which indicate that some hMOs may enhance mucus barrier function through direct modulation of goblet cell function, are studied.

中文翻译:

母乳低聚糖在稳态、促炎条件和内质网应激下不同地调节杯状细胞。

人乳低聚糖(hMO)对肠道屏障功能具有有益作用,但其作用机制尚不清楚。在这里,研究了 hMO 对杯状细胞的影响,这表明一些 hMO 可能通过直接调节杯状细胞功能来增强粘液屏障功能。
更新日期:2019-12-11
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